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Latest SIBO Research Summaries

See the most recent SIBO studies. Sign up to get full access and notifications.

SIBOMar 7, 2026

Using breath tests in gastroenterology: Clear and reliable practitioner guide in 2025.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

n < 30Moderate QualityVerified Source

This is a review article describing how breath tests work in gastroenterology and their current clinical uses in 2025. Breath tests detect gases produced by gut bacteria or digestive enzymes, helping doctors diagnose conditions like carbohydrate malabsorption and bacterial overgrowth without invasive procedures.

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SIBOMar 2, 2026

Alterations in Oro-cecal Transit Time and Small Intestinal Microbiota in Minimal Hepatic Encephalopathy with Small Intestinal Bacterial Overgrowth.

Clinical and translational gastroenterology

n > 100Moderate QualityVerified Source

This study examined 110 cirrhosis patients to see how oral-cecal transit time (OCTT, the time it takes food to travel from mouth to the beginning of the large intestine) relates to small intestinal bacterial overgrowth (SIBO) and minimal hepatic encephalopathy (MHE, a mild form of brain dysfunction caused by liver disease). Researchers found that patients with both MHE and SIBO had significantly slower gut motility and different patterns of bacteria in their small intestine compared to other cirrhosis patients.

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SIBOFeb 20, 2026

Relationship Between Hypothyroidism, Risk of Small Intestinal Bacterial Overgrowth, and Duodenal Microbiome Alterations.

The Journal of clinical endocrinology and metabolism

n = 30-100Moderate QualityVerified Source

This study examined whether people with hypothyroidism (underactive thyroid) have higher rates of SIBO and different bacteria in their small intestine. Researchers found that hypothyroid patients were 2.2 times more likely to develop SIBO over 10 years, but taking levothyroxine (thyroid replacement medication) appeared to reduce this risk. The bacterial makeup in the small intestine differed between hypothyroid and non-hypothyroid patients, particularly in which types of Gram-negative bacteria were present.

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SIBOFeb 2, 2026

Real-world Study of Three-gas Breath Testing Nationwide and the Association With Symptoms.

Journal of clinical gastroenterology

n > 100Moderate QualityVerified Source

This nationwide study of 3,004 people tested three gases in breath tests—hydrogen, methane, and hydrogen sulfide—to see how they relate to digestive symptoms. Hydrogen sulfide levels were strongly linked to diarrhea and more severe symptoms overall, while methane correlated with constipation and hydrogen with diarrhea.

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